2-Chloro-6-(trifluoromethyl)pyridine-3-carbonitrile, 2-Chloro-3-cyano-6-(trifluoromethyl)pyridine - Names and Identifiers
2-Chloro-6-(trifluoromethyl)pyridine-3-carbonitrile, 2-Chloro-3-cyano-6-(trifluoromethyl)pyridine - Physico-chemical Properties
Molecular Formula | C7H2ClF3N2
|
Molar Mass | 206.55 |
Density | 1.51±0.1 g/cm3(Predicted) |
Melting Point | 37~38℃ |
Boling Point | 74~76℃/1mb |
Flash Point | 96.014°C |
Vapor Presure | 0.051mmHg at 25°C |
pKa | -6.61±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.483 |
2-Chloro-6-(trifluoromethyl)pyridine-3-carbonitrile, 2-Chloro-3-cyano-6-(trifluoromethyl)pyridine - Introduction
It is an organic compound with the chemical formula C7H2ClF3N. It is a colorless to pale yellow crystal with a pungent odor.
widely used in the synthesis of pesticide intermediates. It can be used as a raw material for the manufacture of a variety of pesticides such as imidacloprid, the herbicide variety quinalone, etc. In addition, it can also be used as an intermediate for the synthesis of new drugs and bioactive molecules, such as anticancer drugs.
The preparation method of
is generally obtained by reacting 2-chloro-6-trifluoromethylpyridine with chlorocyanin. The specific steps include dissolving 2-chloro-6-trifluoromethylpyridine and chlorocyanin in a suitable solvent, adding a corresponding catalyst, and heating the reaction for a period of time to obtain the product.
Regarding safety, irritant, contact with skin or inhalation may cause irritation and discomfort. Appropriate protective measures should be taken during operation, such as wearing protective gloves, goggles and respiratory protection. Avoid contact with oxidants, strong acids, strong bases and other substances during storage and handling to prevent dangerous reactions.
Last Update:2024-04-09 21:54:55